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  • 专利说明
  • 权利要求
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    • 专利摘要:
    INTRAVASCULAR CATHETER DEVICE. An intravascular catheter device is provided for use during a surgical procedure. The catheter device includes a catheter tube having an expandable portion with a plurality of struts each defining an outer surface. The expandable portion is operable between a closed position, where the expandable portion has a primary diameter, and an open position, where the expandable portion has a greater than the primary diameter. An incision element is provided on the outer surface of at least one of the struts. The element has a blade that extends outwardly in a radial direction from the outer surface of the strut to create an incision in the atherosclerotic material located within a blood vessel when the expandable portion is in the open position.
    公开号:BR112014005721B1
    申请号:R112014005721-4
    申请日:2012-09-13
    公开日:2020-12-29
    发明作者:John P. Pigott
    申请人:John P. Pigott；
    IPC主号:
    专利说明:

    CROSS REFERENCE FOR RELATED ORDERS
    [0001] This application claims the benefit of United States Provisional Application No. 61 / 534,018, filed on September 13, 2011, the disclosure of which is incorporated into this document by reference. BACKGROUND OF THE INVENTION
    [0002] This invention relates in general to intravascular catheters, as they can be used during minimally invasive surgical procedures. In particular, this invention relates to an intravascular catheter, having an expandable portion.
    [0003] Atherosclerosis is a chronic condition in which deateroma plaque accumulates on the inner walls of a blood vessel. As a result, blood vessel walls can become inflamed and, over time, can harden to atherosclerotic lesions in ways that cause a narrowing of the vessel lumen. In severe cases, atherosclerotic lesions can rupture and induce thrombus formation (ie , blood clots), which can prevent blood flow through the narrowed vessel lumen.
    [0004] There are known procedures and devices to treat or otherwise reduce the risks associated with atherosclerosis. For example, an angioplasty is a procedure in which a balloon catheter is inserted into a narrowed region of the vessel's lumen via a delivery catheter. The balloon catheter includes a flexible tube with an inflatable balloon at one end of it. Once positioned in the narrowed region, the balloon is inflated in order to dilate the lumen of the narrowed vessel. Balloon pressure is generally sufficient to compress the accumulated plaque. However, in some cases it would be desirable to fragment atherosclerotic lesions. Thus, it would be desirable to provide an intravascular catheter, having an expandable portion that can be selectively controlled by a user and adapted to create incisions in the atherosclerotic material to facilitate the fragmentation of the material during an angioplasty procedure. SUMMARY OF THE INVENTION
    [0005] This invention relates to an intravascular catheter device for use during a surgical procedure. The catheter device includes a catheter tube having an expandable portion with a plurality of struts each defining an outer surface. The expandable portion is operable between a closed position, where the expandable portion has a primary diameter, and an open position, where the expandable portion has a secondary diameter larger than the primary diameter. An incision element is provided on the outer surface of at least one of the struts. The element has a sharp edge that extends outwardly in a radial direction from the outer surface of the strut to create an incision in the atherosclerotic material located within a blood vessel when the expandable portion is in the open position.
    [0006] Various aspects of this invention will become apparent to those skilled in the art of the following detailed description of the preferred modalities, when read in the light of the accompanying illustrations. BRIEF DESCRIPTION OF THE ILLUSTRATIONS
    [0007] Fig. 1 is a plan view of a catheter device that includes a handling assembly and a catheter tube having an expandable portion, in accordance with the first embodiment of this invention.
    [0008] Fig. 2 is a cross-sectional side view of the handling set taken along cut line 2-2 shown in Fig. 1 when the catheter device is a first mode of operation.
    [0009] Fig. 3 is an enlarged cross-sectional side view of the catheter tube, taken along cut line 3-3 shown in Fig. 1 illustrating the expandable incision portion disposed within a blood vessel.
    [0010] Fig. 4 is a final cross-sectional view of the expandable incision portion taken along the cut line 4-4 shown in Fig. 3.
    [0011] Fig. 5 is a cross-sectional side view of the handling set taken along cut line 2-2 shown in Fig. 1 when the catheter device is a first mode of operation.
    [0012] Fig. 6 is an enlarged cross-sectional side view of the catheter tube, taken along cut line 3-3 shown in Fig. 1 illustrating the expandable incision portion in an open position.
    [0013] Fig. 7 is a final cross-sectional view of the expandable incision portion taken along the cut line 7-7 shown in Fig. 6.
    [0014] Fig. 8 is an enlarged side view of a catheter tube having an expandable incision portion, in accordance with the second embodiment of this invention.
    [0015] Fig. 9 is a side view of the catheter tube, shown in Fig. 8 illustrating the expandable incision portion in an open position.
    [0016] Fig. 10 is a final cross-sectional view of the expandable incision portion taken along the cut line 10-10 shown in Fig. 9.
    [0017] Fig. 11 is an enlarged side view of a catheter tube having an expandable incision portion, in accordance with the third embodiment of this invention.
    [0018] Fig. 12 is a side view of the catheter tube shown in Fig. 11 illustrating the expandable incision portion in an open position.
    [0019] Fig. 13 is a final view of the catheter tube, as shown in Fig. 12.
    [0020] Fig. 14 is an enlarged side view of a catheter tube having an expandable incision portion, in accordance with a fourth embodiment of this invention.
    [0021] Fig. 15 is a side view of the catheter tube, shown in Fig. 14 illustrating the expandable incision portion in an open position.
    [0022] Fig. 16 is a final view of the catheter tube, as shown in Fig. 15. DETAILED DESCRIPTION OF THE INCARNATIONS MODALITIES
    [0023] Referring now to the drawings, a catheter device, generally indicated at 10, in accordance with this invention is illustrated in Fig. 1. The illustrated catheter device 10 is configured to treat or reduce the risks associated with atherosclerosis. In general, the catheter device 10 includes an expandable portion that can be inserted into a blood vessel and expanded to create incisions in the atherosclerotic material that has accumulated in the inner wall of the blood vessel. The incisions facilitate the fragmentation of the atherosclerotic material during a subsequent angioplasty or atherectomy procedure. Despite the catheter device 10, it will be described and illustrated in the context of the treatment of atherosclerosis, it should be appreciated that the catheter device 10 can be used in any desired environment and for any desired purpose.
    [0024] Referring now to Figs. 1 and 2, the illustrated catheter device 10 includes a handling set, generally indicated at 20. The illustrated handling set 20 includes an elongated, cylindrical handling body 21. The handling body 21 Alternatively may have any other shape suitable for easy handling by a surgeon. In addition, the handling body 21 can be made of any suitably rigid material including, but not limited to, stainless steel or polymers.
    [0025] As shown in Fig. 2, the illustrated handling body 21 defines an inner chamber 22. A passageway 23 extends into a final portion of the handling body 21 for communication with the inner chamber 22. The handling body 21 additionally includes a groove 24 that extends through a side wall for communication with the inner chamber 22. The illustrated groove 24 can be any length or width as desired. As shown in Fig. 1, an indicator 24A can be provided on the handling body 21 adjacent to the groove 24. For example, the indicator 24A can be a visual scale or any other means of indication, the purpose of which will be explained below.
    [0026] The illustrated handling set 20 also includes a control member 25 that is supported on the handling body 21 for sliding movement within the groove 24. For example, the control member 25 is movable between an advanced position (shown in Fig 2), a rear position (shown in Fig. 5) or any position between them, which will be explained below. As shown in Fig. 2, the illustrated control member 25 includes a base portion 26 is disposed within the inner chamber 22 of the handling body 21. The base portion 26 may define an outer transverse shape that generally corresponds to a transverse shape of the chamber 22, although this is not mandatory. Alternatively (or, in addition), the control member 25 can be movably supported on the handling body 21 by a bearing, a bushing, a guide rail or any other structural means. In other embodiments, the control member 25 can be supported by rotational movement, pivoting movement or any other type of movement relative to the handling body 21, the purpose of which will become evident below. The visual indicator 24A, described above, is configured to identify the relative position of the control member 25 with respect to the handling body 21.
    [0027] The handling set 20 also includes a locking mechanism 27 that is configured to temporarily hold the control member 25 in the desired position, although this is not mandatory. As shown in Fig. 2, the illustrated locking mechanism 27 includes a plurality of protrusions that are spaced apart from each other along the inner surface of the groove 24. The control member 25 engages in a frictional manner with the protrusions to hold the member control 25 in the desired position. Alternatively, the locking mechanism 27 can be a threaded screwing element, a pivoting latch, a pushbutton release or any other mechanism that is configured to secure the control member 25 in the desired position.
    [0028] Referring now to Figs. 1 to 3, the illustrated catheter device 10 also includes a catheter tube 30 that extends from the handling assembly 20. The catheter tube 30 is a member, elongated and flexible, having a proximal end that is attached to the handling assembly 20 and a distal end extending from there. Catheter tube 30 can be made of any biocompatible material, including, but not limited to, polyvinyl chloride, polyethylene, nitinol or stainless steel. In addition, catheter tube 30 can have any outside diameter, length or wall thickness.
    [0029] As shown in Fig. 2, the proximal end of the catheter tube 30 is attached to the handling body 21 and communicates with the internal cavity 22 through passage 23. The catheter tube 30 can be attached to the body of handling 21 using a flanged connection, a fused connection, an adhesive, a snap-fit connection, a threaded connection or any other gripping means. Alternatively, the catheter tube 30 can be attached to the handling body 21 using a connector or any other type of fixation device.
    [0030] As shown in Figs. 1 and 3, an expandable portion 32 is provided at the distal end of the catheter tube 30. The illustrated expandable portion 32 is a cylindrical member having a longitudinal axis. The expandable portion 32 can be made of a generally resistant material that is capable of flexing between various positions, such as polyvinyl chloride, polyethylene, nitinol or stainless steel. The expandable portion 32 can be attached to the catheter tube 30 in any form, including, but not limited to, a molten connection, an adhesive, a snap fit connection, a threaded connection or any other gripping means. Alternatively, the expandable portion 32 can be integrally formed in the catheter tube 30. In addition, the expandable portion 32 can have any outside diameter, length or wall thickness.
    [0031] The illustrated expandable portion 32 has a pair of struts 34A and 34B. The illustrated struts 34A and 34B are separated by a pair of longitudinally extending slots 35A and 35B that extend through the side walls of the expandable portion 32. As shown in Fig. 4, the slots 35A and 35B are equally spaced apart in around the circumference of the expandable portion 32 such that the strut 34A and 34B have the same circumferential widths, although this is not mandatory. Struts 34A and 34B can be of any length, circumferential width or transverse shape, as desired.
    [0032] As shown in Figs. 3 and 4, the illustrated expandable portion 32 also includes a pair of incision elements 36 which are respectively provided along external surfaces of the struts 34A and 34B. The incision elements 36 can be atherotomes or other insertion members having a sharp edge shape, for example, which are configured to create incisions in the atherosclerotic material, as will be explained below. The illustrated incision elements 36 extend in parallel with the longitudinal axis of the expandable portion 32 and, externally, in a resulting radial direction. The incision elements 36 are equally spaced apart around the circumference of the expandable portion 32. The expandable portion 32 can, however, have any number of configuration of incision elements 36 provided around the circumference thereof. In addition, the incision elements 36 can have any transverse shape, longitudinal length or height and can be made of any suitable material, including, but not limited to, tempered steel, stainless steel, high carbon steel or ceramic. The incision elements 36 can be molded with the struts 34A and 34B or can otherwise be attached to them in any way, such as, for example, using a welded or solder connection, an adhesive or any other means of attachment .
    [0033] The distal end of the expandable portion 32 can optionally include a tip member 38. The illustrated tip member 38 has a generally tapered shape that facilitates insertion of catheter tube 30 into a blood vessel 50 (see Figs 3 and 4) and subsequent trips through it. Point member 38 may, however, have any desired shape. An opening can extend axially through the nose member 38, the purpose of which will be explained below. The pointed member 38 can be integrally formed with the expandable portion 32 or can be attached to it, such as with an adhesive or the like. In addition, the pointed member 38 can be made of any biocompatible material, including, but not limited to, polyvinyl, polyethylene, nitinol or polyether block starch.
    [0034] As shown in Figs. 2 to 4, the illustrated catheter device 10 also includes an inner sleeve 40, although this is not mandatory. The inner sleeve 40 is a flexible, tubular member that is supported by the sliding movement inside the catheter tube 30, the purpose of which will be explained below. The inner sleeve 40 can be made of any biocompatible material, including, but not limited to, polyvinyl chloride, polyethylene, nitinol, stainless steel or a fabric material. In addition, the inner sleeve 40 can have any outside diameter, length or wall thickness. The inner sleeve 40 need not be a tubular member, but may alternatively be a solid wire, a braided wire or the like.
    [0035] As shown in Fig. 2, a proximal end of the inner sleeve 40 extends from the catheter tube 30 and into the inner chamber 22 of the handling body 21. The proximal end of the inner sleeve 40 is attached to the portion of base 26 of control member 25 for sliding movement therewith, the purpose of which will be explained below. The inner sleeve 40 can be attached to the base portion 26 by a flanged connection, a molten connection, an adhesive, a threaded connection or any other fastening means.
    [0036] As shown in Fig. 3, the inner sleeve 40 extends across a total length of the catheter tube 30. A distal end of the inner sleeve 40 that is opposite the handling assembly 20 is attached to the tip member 38 , which in turn is attached to the expandable portion 32. The inner sleeve 40 can be attached to the pointed member 38 in any way, including, but not limited to, a molten connection, an adhesive, a screw fastener or the like .
    [0037] Referring again to Figs. 1 and 2, the illustrated catheter device 10 also includes a protective sheath 42 which is supported for sliding movement along an outer surface of the catheter tube 30, although this is not mandatory. The protective sheath 42 can be made of any biocompatible material, including, but not limited to, polyvinyl, polyethylene, nitinol or stainless steel. In addition, the protective sheath 42 can have any outside diameter, length or wall thickness. The purpose of protective sheath 42 will be explained below.
    [0038] The illustrated protective sheath 42 includes a flange 44 that facilitates the sliding movement of the protective sheath 42 in relation to the catheter tube 30. The illustrated flange 44 is an annular member that is located at one end of the protective sheath 42 closest to the handling set 20. Flange 44 may be integrally formed with protective sheath 42 or may otherwise be attached to them in any manner, such as with an adhesive or the like. This should be appreciated such that the flange 44 can be of any shape or, alternatively, it can be configured to perform the functions described in this document and below.
    [0039] The operation of the catheter device 10 will now be described with reference to Figs. 1 to 7. Referring initially to Figs. 1 to 4, the catheter device 10 is illustrated in a first operational mode. In the first operating mode, the control member 25 in the handling set 20 is located in an advanced position relative to the handling body 21. The inner sleeve 40 extends fully into the catheter tube 30 such that the expandable portion 32 is in a position closed, as shown in Figs. 3 and 4. In the closed position, the struts 34A and 34B are generally parallel to each other and with the inner sleeve 40. Slots 35A and 35B (illustrated by dashed lines in Fig. 3) remain in a generally closed configuration. As such, the expandable portion 32 defines an initial diameter D1, which is generally the same diameter as the remaining length of the catheter tube 30. The initial diameter D1 of the expandable portion 32, however, can be any desired dimension.
    [0040] When the catheter device 10 is the first mode of operation, the distal end of the catheter tube 30 can be percutaneously inserted into a blood vessel 50, as shown in Figs. 3 and 4. The illustrated catheter tube 30 is then advanced through blood vessel 50 along a guidewire 52, which extends through catheter device 10. For example, guidewire 52 can fully extend through sleeve 40, inside the inner chamber 22 of the handling body 21, and a rear end of the handling assembly 20 comes out (see Fig. 2). Catheter tube 30 is advanced along guide wire 52 until expandable portion 32 is positioned in a narrowed region of blood vessel 50 caused by atherosclerotic material 54. Alternatively, catheter tube 30 can be inserted into blood vessel 50 and guided into it by a delivery catheter (not shown) or any other appropriate procedure. During the insertion and advancement of the catheter tube 30 through the blood vessel 50, the optional protective sheath 42 is preferably positioned on the expandable portion 32, thus preventing the incision elements 36 from coming into contact with the internal walls of the vessel blood 50.
    [0041] Once the expandable portion 32 is positioned in the narrowed region of the blood vessel 50, the incision elements 36 can be exposed by sliding the protective sheath 42 back from the distal end of the catheter tube 30, as indicated by the direction arrows on the Fig. 3. The illustrated protective sheath 42 can be moved this way by pulling the flange 44 towards the handling set 20, which is indicated by the direction arrows in Fig. 2.
    [0042] Referring now to Figs. 5 to 7, the catheter device 10 is illustrated in a second operational mode. To reach the second operating mode, the control member 25 is moved from the forward position to the recessed position, as indicated by the direction arrow in Fig. 5. As the control member 25 is moved to the recessed position, the inner sleeve 40 is extracted from the inside of the catheter tube 30, thereby decreasing the relative length of the inner sleeve 40 in relation to the catheter tube 30. The distal end of the inner sleeve 40 is attached to the tip member 38, as described above, causing the the expandable portion 32 to become axially compressed between the tip member 38 and the distal end of the catheter tube 30. As a result, the strut 34A and 34B curves or expands outwardly in an arcuate style, thus defining an open position. In the open position, the expandable portion 32 defines a secondary diameter D2 that is greater than the initial diameter D1 when the expandable portion 32 is in the closed position. As shown in Fig. 6, the incision elements 36 are respectively positioned along the outermost surfaces radially of the struts 34A and 34B. In addition, the outer surfaces and most struts 34A and 34B can define a generally flat part along a respective length in the open position, the purpose of which will be explained below, although this is not mandatory. It should be appreciated that struts 34A and 34B can be of any length such that the expandable portion 32 can reach a desired total secondary diameter D2 in the open position.
    [0043] During the operation of the catheter device 10, the secondary diameter D2 can be increased or decreased by the selective movement of the control member 25 between the forward and backward positions. For example, a larger secondary diameter D2 can be achieved by moving the control member 25 further towards the recessed position. On the other hand, a smaller secondary diameter D2 can be achieved by moving the control member 25 further towards the forward position. The visual indicator 24A can be used to identify the secondary diameter D2 snapshot of the expandable portion 32. Alternatively (or in addition), the struts 34A and 34B can be tilted in the open position to automatically expand outward to the secondary diameter D2 when the protective sheath 42 is slid back from the expandable portion 32. As such, sliding movement of the protective sheath 42 in relation to the struts 34A and 34B can be used to selectively control the secondary diameter D2. In this configuration, the inner sleeve 40 and the moving components of the handling assembly 20 may not be necessary.
    [0044] When the catheter device 10 is the secondary operating mode, the expandable portion 32 can be pulled along the guide wire 52 through the region of the narrowing of the blood vessel 50. This can be done by pulling on the handling set 20. In doing so, the incision elements 36 engage the atherosclerotic material 54 and create longitudinal incisions 56 therein. As shown in Figs. 6 and 7, the area of the outer surface of the arched shaped strut 34A and 34B, which is adjacent to the element of 36s, is configured to guide along a surface of the atherosclerotic material 54, thereby limiting the depth of the incisions 56 and preventing that the incision members 36 cut through the walls of the blood vessel 50. The expandable portion 32 can be moved any distance along the guidewire 52 to create incisions 56 having any desired length. After the incisions 56 are made in the atherosclerotic material 54, the catheter device 10 can be returned to the first operating mode (shown in Figs. 1 to 4), moving the control member 25 to the forward position. In doing so, the expandable portion 32 returns to the closed position. The protective sheath 42 can be slid over the expandable portion 32 and the catheter tube 30 can be removed from the blood vessel 50.
    Alternatively, catheter device 10 can be used to create additional incisions 56 in atherosclerotic material 54. For example, after catheter device 10 has been returned to the first operational mode, expandable portion 32 can be relocated within the narrowed region of blood vessel 50. The catheter tube 30 can then be rotated into blood vessel 50 by rotating the handling assembly 20 to align the incision elements 36 with other parts of the atherosclerotic material 54. The previous steps can then be repeated any number of times to make several passes through the region of the narrowed blood vessel 50 and creates additional incisions in the atherosclerotic material 54.
    [0046] Thus, it should be appreciated that the illustrated catheter device 10 is advantageous in many ways. In one example, the secondary diameter D2 of the expandable portion 32 can be selectively controlled by operating the handling assembly 20 or sliding movement of the protective sheath 42. This allows the catheter device 10 to be adapted for use in blood vessels 50 of different sizes and varied diameters. In another example, the illustrated catheter device 10 can apply different magnitudes of radial forces to the atherosclerotic material 54 by controlling the amount of force being applied to the control member 25 in the handling set 20. This allows the catheter device 10 to generate force enough radial to create incisions 56 in atherosclerotic material 54 while reducing the potential to tear the walls of blood vessel 50. In another example, catheter device 10 can be used to make any number of passes during a single procedure to make multiple incisions 56 in atherosclerotic material 54 of different lengths and shapes.
    [0047] Referring now to Figs. 8 to 10, a catheter tube 130 having an expandable portion 132 is shown, in accordance with the second embodiment of this invention. The catheter tube 130 and the expandable portion 132 can include any structural features as described and illustrated above in the previous embodiment, although this is not mandatory. Similar characteristics have been numbered with common reference numbers, but have been increased by 100 (ie 110, 120, 130, etc.). It should be appreciated that similar characteristics are structured in the same way, operate in the same way, and / or have the same function, unless otherwise indicated by drawings or this specification.
    [0048] For example, catheter tube 130 may extend from a handling assembly (not shown) as described above in the first embodiment. The expandable portion 132 is provided at a distal end of catheter tube 130 and may include a tip member 138. [0048] Catheter tube 130 may also include an inner sleeve 140 and a protective sheath (not shown), which is also described above in the first modality.
    [0049] In the illustrated embodiment, however, the expandable portion 132 includes four struts 134A, 134B, 134C and 134D which are respectively separated by four extending longitudinally across 135A, 135B, 135C and 135D. The illustrated struts 134A, 134B, 134C and 134D each include an element of 136, although this is not mandatory. It should be appreciated that the expandable portion 132 can have any number or configuration of the struts and incision elements as desired.
    [0050] As shown in Fig. 8, the illustrated expandable portion 132, additionally, includes flush portions 160 which respectively extend to the outer surfaces of struts 134A, 134B, 134C and 134D. For example, the strut 134A and 134B, 134C, 134D can be slightly curved inwardly for the inner sleeve 140 when in closed position, or alternatively it can be reduced in thickness along a central part to create the embedded portions 160. The illustrated incision elements 136 are respectively disposed within the embedded portions 160. Thus, when the catheter tube 130 is inserted into a blood vessel, as described above, the embedded portions 160 contribute to prevent the elements of 136 from coming into contact with the internal walls of the blood vessel. On the other hand, when the expandable portion 132 is expanded to an open position, as explained below, the elements of 136 become exposed by the embedded portions 160. It should be appreciated that the embedded portions 160 can eliminate or reduce the need for the sheath protection (not shown).
    [0051] The expandable portion 132 can be operated between a closed position (shown in Fig. 8) and an open position (shown in Figs. 9 and 10) by the selective movement of the inner sleeve 140 relative to the catheter tube 130, as described above in the first mode. Alternatively (or in addition), struts 134A, 134B, 134C and 134D can be tilted in the open position. In such an embodiment, the protective sheath (not shown) can be used for the effect of movement of the expandable portion 132 between the closed position and the open position.
    [0052] Referring now to Figs. 11 to 13, a catheter tube 230 having an expandable portion 232 is illustrated, in accordance with a third embodiment of this invention. The catheter tube 230 and the expandable portion 232 can include any structural features as described and illustrated above in the previous embodiments, although this is not mandatory. Similar characteristics have been listed with common reference numbers, but have been increased by 200 (ie 210, 220, 230, etc.). It should be appreciated that similar features are structured in the same way, operating in the same way, and / or have the same function, unless otherwise indicated by drawings or this specification.
    [0053] For example, catheter tube 230 may extend from a handling assembly (not shown) as described above in the first mode. The expandable portion 232 is provided at a distal end of the catheter tube 230 and includes a pair of struts 234A and 234B which are separated by a pair of longitudinally extending slots 235A and 235B. The catheter tube 230 may also include a pointed member238, an inner sleeve 240 and a protective sheath (not shown), which is described above in the first embodiment.
    [0054] In the illustrated embodiment, however, the expandable portion 232 includes a first pair of weakened regions 237A, 237B and a second pair of weakened regions 239A, 239B that are respectively located at opposite ends of struts 234A and 234B. As illustrated weakened regions 237A, 237B and 239A, 239B are formed by enlarged openings that extend through the side walls of the expandable portion 232 which function as hinges. The weakened regions 237A, 237B and 239A, 239B can help reduce the amount of flexural stress on the side walls of the expandable portion 232 when struts 234A and 234B are moved to an open position. Struts 234A and 234B can include any number or configuration of the weakened regions. In addition, it should be appreciated that any of the other modalities in this disclosure may also include weakened regions 237A, 237B and 239A, 239B.
    [0055] The illustrated struts 234A and 234B generally remain flat along lengths in a closed position (shown in Fig. 11) and an open position (shown in Figs. 12 and 13) in order to form an apex, although such a configuration not needed. The elements of 236 are provided along the flat portion generally of the respective struts 234A and 234B. As such, incision elements 236 can also function as reinforcing members to increase the strength of struts 234A and 234B. In addition, this configuration can reduce the amount of stress in the connection between the elements of 236 and the struts 234A and 234B, which may otherwise be caused by bending of the struts 234A and 234B.
    [0056] As shown in Fig. 12, end portions of the elements of 236 may extend beyond the apex that is formed by each of the respective struts 234A and 234B. This configuration can increase the effective height of the elements 236 when the expandable portion 232 is in the open position. As such, the elements of 236 may have a reduced blade height when the expandable portion 232 is in the closed position, which can eliminate the need for the protective sheath (not shown).
    [0057] The expandable portion 232 can be operated between the closed position and the open position by the selective movement of the inner sleeve 240 in relation to the catheter tube 230, as described above in the first embodiment. Alternatively (or in addition), struts 234A, 234B, can be tilted in the open position. In such an embodiment, the protective sheath (not shown) can be used for the effect of movement of the expandable portion 232 between the closed position and the open position.
    [0058] Referring now to Figs. 14 to 16, a catheter tube 330 having an expandable portion 332 is illustrated, in accordance with a fourth embodiment of this invention. The catheter tube 330 and the expandable portion 332 can include any structural features as described and illustrated above in the previous embodiments, although this is not mandatory. Similar characteristics have been listed with common reference numbers, increased by 300 (ie 310, 320, 330, etc.). It should be appreciated that similar characteristics are structured in the same way, operate in the same way, and / or have the same function, unless otherwise indicated by drawings or this specification.
    [0059] For example, catheter tube 330 may extend from a handling assembly (not shown) as described above in the first embodiment. The expandable portion 332 is provided at a distal end of catheter tube 330 and may include a tip member 338. Catheter tube 330 may also include an inner sleeve 340 that is attached to member 338 and a protective sheath (not shown) , which is also described above in the first modality.
    [0060] In the illustrated embodiment, however, the expandable portion 332 includes a pair of struts 334A and 334B that are supported thereon in a swing form (i.e., not connected to each other or to the tip member 338 at its distal ends ), the purpose of which will be explained below. The struts 334A and 334B are separated by a pair of longitudinally extending slits 335A and 335B extending from the expandable portion 332. A pair of incision elements 336 respectively is provided along the outer surfaces of the struts 334A and 334B. It should be appreciated, however, that the expandable portion 332 can have any number or configuration of the struts and elements as desired.
    [0061] As shown in Figs. 15 and 16, the illustrated struts 334A and 334B are supported on the expandable portion 332 so that they can be spread flat in a Y-shaped configuration. For example, struts 334A and 334B can be spread flat by removing the inner sleeve 340 at the inside the catheter tube 330, as described above in the first embodiment. In doing so, the tip member 338 slides along internal surfaces of struts 334A and 334B and pivots them externally. Alternatively (or in addition), struts 334A, 334B, can be flattened in the open position. In such an embodiment, the protective sheath (not shown) can be used for the effect of movement of the expandable portion 232 between the closed position and the open position.
    [0062] Struts 334A and 334B generally remain horizontally along their respective lengths both in a closed position (shown in Fig. 14) and the open flat position, although this is not mandatory. As such, incision elements 336 can also function as resistance members to increase the strength of struts 334A and 334B. In addition, this configuration can reduce the amount of stress in the connection between the incision elements 336 and the struts 334A and 334B, which may otherwise be caused by curvature of the struts 334A and 334B.
    [0063] As shown in Fig. 15, end portions of the incision elements 336 may extend beyond the distal ends of the respective struts 334A and 334B. This configuration can increase the effective height of the incision elements 336 when the expandable portion 332 is in the open flat position. As such, the incision elements 336 may have a reduced blade height when the expandable portion 332 is in the closed position, which can eliminate the need for the protective sheath (not shown).
    [0064] The principle and mode of operation of this invention have been explained and illustrated in its preferred modalities. However, it must be understood that this invention can be practiced in a way other than that specifically explained and illustrated without departing from its spirit or scope.
    权利要求:
    Claims (11)
    [0001]
    1. Intravascular catheter device (10), characterized by the fact that it comprises: a flexible catheter tube (30, 130, 230, 330), including a selective expandable portion (32, 132, 232, 332) having a plurality of struts (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) each defining an outer surface, the expandable portion (32, 132, 232, 332) being operable between a closed position, where the expandable portion (32, 132, 232, 332) has a primary diameter (D1), and an open position, where the expandable portion (32, 132, 232, 332) has a secondary diameter (D2) greater than the primary diameter (D1); an inner sleeve (36, 136, 236, 336) that is supported by the sliding movement inside the flexible catheter tube (30, 130, 230, 330), the inner sleeve (36, 136, 236, 336) is fixed to a distal end of the expandable portion (32, 132, 232, 332) to selectively control the movement of the struts (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) between the closed position and the open position; and an incision element (36, 136, 236, 336) provided on the outer surface of at least one of the struts (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B), the incision element (36, 136 , 236, 336) having a sharp edge that extends outwardly from the outer surface of the strut (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) and in parallel with a longitudinal axis of the expandable portion (32, 132 , 232, 332) such that the incision element (36, 136, 236, 336) is configured to create an incision in the atherosclerotic material (54) located within a blood vessel (50) when the expandable portion (32, 132, 232 , 332) is in the open and axially retracted position such that the sharp edge is configured to run parallel to the longitudinal axis of the blood vessel (50).
    [0002]
    2. Intravascular catheter device, according to claim 1, characterized by the fact that the struts (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) are respectively linked to each other at their opposite ends and curved outwardly in open position.
    [0003]
    3. Intravascular catheter device according to claim 2, characterized in that the external surface of each strut (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) defines an arcuate member, having an area of surface adjacent to the incision element (36, 136, 236, 336) which limits the depth of an incision created by the incision element and prevents the incision element from cutting through a blood vessel wall (50).
    [0004]
    4. Intravascular catheter device according to claim 1, characterized in that the catheter tube (30, 130, 230, 330) extends from a handling assembly (20) and an inner sleeve (36, 136, 236, 336) is connected to a control member (25) which is movably supported in the handling set (20) for selective control movement of an expandable portion (32, 132, 232, 332) between the closed position and the open position.
    [0005]
    5. Intravascular catheter device according to claim 4, characterized by the fact that the handling set (20) includes an indicator that identifies the relative position of the control member (25) in the handling set.
    [0006]
    6. Intravascular catheter device according to claim 4, characterized in that the handling set (20) includes a locking mechanism (27) to secure the control member (25) in a selected position in the handling set (20).
    [0007]
    7. Intravascular catheter device according to claim 2, characterized by the fact that the expandable portion (32, 132, 232, 332) defines weakened regions (237A, 237B, 239A and 239B) that are, respectively, located at ends opposite each strut (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) and adapted to the function as hinges.
    [0008]
    8. Intravascular catheter device according to claim 2, characterized in that a portion of each strut (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) remains generally flat over a length both at closed and open positions, and the incision element (36, 136, 236, 336) is supported on the flat portion of at least one strut (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B).
    [0009]
    9. Intravascular catheter device according to claim 2, characterized in that the struts (34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) are inclined in the open position.
    [0010]
    An intravascular catheter device according to claim 9, characterized in that it additionally includes a protective sheath (42) which is supported for the sliding movement along an outer surface of the catheter tube (30, 130, 230, 330) to control the movement of the expandable portion (32, 132, 232, 332) between the closed position and the open position.
    [0011]
    11. Intravascular catheter device, characterized by the fact that it comprises: a handling set (20), including a control member (25) movably supported on it; a flexible catheter tube (30, 130, 230, 330), extending from the handling set (20) and including an expandable portion (32, 132, 232, 332) defining a longitudinal axis and having a plurality of anchors ( 34A, 34B, 134A, 134B, 234A, 234B, 334A, 334B) each defining an external surface, the expandable portion (32, 132, 232, 332) being operable between a closed position, where the expandable portion (32, 132 , 232, 332) has a primary diameter, and an open position, in which the expandable portion (32, 132, 232, 332) has a diameter that is larger than the primary diameter; an incision element (36, 136, 236, 336) provided on the outer surface of at least one of the struts (34A, 34B, 134A, 134B, 234A, 5 234B, 334A, 334B), the incision element (36, 136 , 236, 336) having a sharp edge that extends in parallel with the longitudinal axis of the expandable portion (32, 132, 232, 332) and, externally, in a radial direction of the outer surface such that the sharp edge is configured to extend parallel to the longitudinal axis of a blood vessel (50) when 10 inserted into said blood vessel (50); and an inner sleeve (36, 136, 236, 336) which is supported for a sliding movement inside the flexible catheter tube (30, 130, 230, 330), where the inner sleeve (36, 136, 236, 336) is connected between the control member (25) and the handling set (20) and a distal end 15 of the expandable portion (32, 132, 232, 332) to selectively control the movement of the expandable portion (32, 132, 232, 332 ) between the closed position and the open position.
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    同族专利:
    公开号 | 公开日
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    EP2755714A1|2014-07-23|
    JP2018023840A|2018-02-15|
    US20200093509A1|2020-03-26|
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    JP2014531243A|2014-11-27|
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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US2655154A|1952-12-05|1953-10-13|Richter Bruno|Valvulotome|
    US3557794A|1968-07-30|1971-01-26|Us Air Force|Arterial dilation device|
    US3704711A|1971-06-30|1972-12-05|Sang C Park|Catheter|
    US4273128A|1980-01-14|1981-06-16|Lary Banning G|Coronary cutting and dilating instrument|
    US4564014A|1980-01-30|1986-01-14|Thomas J. Fogarty|Variable length dilatation catheter apparatus and method|
    US4292974A|1980-01-30|1981-10-06|Thomas J. Fogarty|Dilatation catheter apparatus and method|
    US4654027A|1985-10-30|1987-03-31|Dragan William B|Vascular dilating device|
    US5728067A|1989-01-30|1998-03-17|C. R. Bard, Inc.|Rapidly exchangeable coronary catheter|
    EP0380873B1|1989-01-30|1994-05-04|C.R. Bard, Inc.|Rapidly exchangeable coronary catheter|
    US5282484A|1989-08-18|1994-02-01|Endovascular Instruments, Inc.|Method for performing a partial atherectomy|
    US5156610A|1989-08-18|1992-10-20|Evi Corporation|Catheter atherotome|
    ES2079483T3|1989-08-18|1996-01-16|Evi Corp|CATHETER ATEROTOME.|
    US5211651A|1989-08-18|1993-05-18|Evi Corporation|Catheter atherotome|
    US5100425A|1989-09-14|1992-03-31|Medintec R&D Limited Partnership|Expandable transluminal atherectomy catheter system and method for the treatment of arterial stenoses|
    US5030201A|1989-11-24|1991-07-09|Aubrey Palestrant|Expandable atherectomy catheter device|
    US5074871A|1989-12-07|1991-12-24|Evi Corporation|Catheter atherotome|
    US5178625A|1989-12-07|1993-01-12|Evi Corporation|Catheter atherotome|
    US5154724A|1990-05-14|1992-10-13|Andrews Winston A|Atherectomy catheter|
    US5244619A|1991-05-03|1993-09-14|Burnham Warren R|Method of making catheter with irregular inner and/or outer surfaces to reduce travelling friction|
    US5224945A|1992-01-13|1993-07-06|Interventional Technologies, Inc.|Compressible/expandable atherectomy cutter|
    US5246421A|1992-02-12|1993-09-21|Saab Mark A|Method of treating obstructed regions of bodily passages|
    WO1993019679A1|1992-04-07|1993-10-14|The Johns Hopkins University|A percutaneous mechanical fragmentation catheter system|
    EP0888758B1|1992-05-08|2003-08-20|Schneider Inc.|Esophageal stent|
    US5250060A|1992-06-26|1993-10-05|Carbo Paul L|Angioplasty apparatus|
    US5312427A|1992-10-16|1994-05-17|Shturman Cardiology Systems, Inc.|Device and method for directional rotational atherectomy|
    US5571122A|1992-11-09|1996-11-05|Endovascular Instruments, Inc.|Unitary removal of plaque|
    US5836868A|1992-11-13|1998-11-17|Scimed Life Systems, Inc.|Expandable intravascular occlusion material removal devices and methods of use|
    US5318576A|1992-12-16|1994-06-07|Plassche Jr Walter M|Endovascular surgery systems|
    GB9314640D0|1993-07-15|1993-08-25|Salim Aws S M|Tunnellimg catheter|
    US6719773B1|1998-06-01|2004-04-13|Kyphon Inc.|Expandable structures for deployment in interior body regions|
    US5591194A|1994-02-18|1997-01-07|C. R. Bard, Inc.|Telescoping balloon catheter and method of use|
    WO1996039997A2|1995-06-07|1996-12-19|Stentco, Inc.|Device and method for delivering and deploying intraluminal devices|
    US5456694A|1994-05-13|1995-10-10|Stentco, Inc.|Device for delivering and deploying intraluminal devices|
    US5514093A|1994-05-19|1996-05-07|Scimed Life Systems, Inc.|Variable length balloon dilatation catheter|
    ES1030202Y|1995-02-20|1996-01-16|Medina Fernandez Aceytuno Alfo|BALL CATHETER WITH IMPROVED TUBULAR DEVICE FOR USE IN THE TREATMENT OF VASCULAR STENOSIS.|
    US5728123A|1995-04-26|1998-03-17|Lemelson; Jerome H.|Balloon actuated catheter|
    US5658309A|1995-05-01|1997-08-19|C. R. Bard, Inc.|Guidewire/inflation tube locking apparatus and method of use|
    WO1996040349A1|1995-06-07|1996-12-19|Advanced Cardiovascular Systems, Inc.|Sheath for an adjustable length balloon|
    US5792158A|1995-11-15|1998-08-11|Lary; Banning Gray|University dilator with expandable incisor|
    US5697944A|1995-11-15|1997-12-16|Interventional Technologies Inc.|Universal dilator with expandable incisor|
    US5733296A|1996-02-06|1998-03-31|Devices For Vascular Intervention|Composite atherectomy cutter|
    CA2209366C|1996-09-13|2004-11-02|Interventional Technologies, Inc.|Incisor-dilator with tapered balloon|
    US5800450A|1996-10-03|1998-09-01|Interventional Technologies Inc.|Neovascularization catheter|
    US5968064A|1997-02-28|1999-10-19|Lumend, Inc.|Catheter system for treating a vascular occlusion|
    US6217549B1|1997-02-28|2001-04-17|Lumend, Inc.|Methods and apparatus for treating vascular occlusions|
    US6488673B1|1997-04-07|2002-12-03|Broncus Technologies, Inc.|Method of increasing gas exchange of a lung|
    AU9693198A|1997-10-10|1999-05-03|Hearten Medical, Inc.|A catheter device for abrading a patent foramen ovale and method of using the device|
    US5961536A|1997-10-14|1999-10-05|Scimed Life Systems, Inc.|Catheter having a variable length balloon and method of using the same|
    US6666874B2|1998-04-10|2003-12-23|Endicor Medical, Inc.|Rotational atherectomy system with serrated cutting tip|
    US6071287A|1998-12-23|2000-06-06|Medtronic, Inc.|Introducer for single operator stent delivery system|
    US6364867B2|1999-07-01|2002-04-02|Catheter Innovations, Inc.|Anti-clotting methods and apparatus for indwelling catheter tubes|
    US6283947B1|1999-07-13|2001-09-04|Advanced Cardiovascular Systems, Inc.|Local drug delivery injection catheter|
    US8328829B2|1999-08-19|2012-12-11|Covidien Lp|High capacity debulking catheter with razor edge cutting window|
    US6527740B1|1999-12-22|2003-03-04|Advanced Cardiovascular Systems, Inc.|Medical regrooming and drug delivery device|
    US7517352B2|2000-04-07|2009-04-14|Bacchus Vascular, Inc.|Devices for percutaneous remote endarterectomy|
    ES2365208T3|2000-07-24|2011-09-26|Jeffrey Grayzel|CATHETER WITH RIGIDIZED BALLOON FOR DILATATION AND IMPLEMENTATION OF ENDOVASCULAR PROSTHESIS.|
    US6884257B1|2000-11-28|2005-04-26|Advanced Cardiovascular Systems, Inc.|Stent delivery system with adjustable length balloon|
    US6692466B1|2000-12-21|2004-02-17|Advanced Cardiovascular Systems, Inc.|Drug delivery catheter with retractable needle|
    US6599267B1|2000-12-22|2003-07-29|Advanced Cardiovascular Systems, Inc.|Transluminal injection device for intravascular drug delivery|
    WO2002078511A2|2001-03-30|2002-10-10|Nanopass Ltd.|Inflatable medical device with combination cutting elements and drug delivery conduits|
    JP4345478B2|2001-08-08|2009-10-14|株式会社カネカ|Dilatation catheter|
    FR2830455B1|2001-10-09|2004-06-25|Saphir Medical|CATHETER WITH RETRACTABLE PERFORATING OR STITCHING TOOL|
    US7507245B2|2001-10-19|2009-03-24|Cardiovascular Systems, Inc.|Rotational angioplasty device with abrasive crown|
    US6951566B2|2002-01-25|2005-10-04|Scimed Life Systems, Inc.|Reciprocating cutting and dilating balloon|
    US6796989B2|2002-05-06|2004-09-28|Renan Uflacker|Intraluminal cutter for vascular, biliary and other applications|
    US20040082947A1|2002-10-25|2004-04-29|The Regents Of The University Of Michigan|Ablation catheters|
    US7329267B2|2002-12-23|2008-02-12|Boston Scientific Scimed, Inc.|Medical cutting devices and methods of use|
    US7686824B2|2003-01-21|2010-03-30|Angioscore, Inc.|Apparatus and methods for treating hardened vascular lesions|
    US8080026B2|2003-01-21|2011-12-20|Angioscore, Inc.|Apparatus and methods for treating hardened vascular lesions|
    US7131981B2|2003-03-25|2006-11-07|Angiodynamics, Inc.|Device and method for converting a balloon catheter into a cutting balloon catheter|
    US8070761B2|2003-04-10|2011-12-06|Boston Scientific Scimed, Inc.|Vessel occluding material extractor|
    US7279002B2|2003-04-25|2007-10-09|Boston Scientific Scimed, Inc.|Cutting stent and balloon|
    US20040267345A1|2003-06-30|2004-12-30|Lorenzo Juan A.|Balloon catheter with self-centering tip|
    US7887557B2|2003-08-14|2011-02-15|Boston Scientific Scimed, Inc.|Catheter having a cutting balloon including multiple cavities or multiple channels|
    US20050055077A1|2003-09-05|2005-03-10|Doron Marco|Very low profile medical device system having an adjustable balloon|
    DE202004021943U1|2003-09-12|2013-05-13|Vessix Vascular, Inc.|Selectable eccentric remodeling and / or ablation of atherosclerotic material|
    US8043311B2|2003-12-22|2011-10-25|Boston Scientific Scimed, Inc.|Medical device systems|
    US7326236B2|2003-12-23|2008-02-05|Xtent, Inc.|Devices and methods for controlling and indicating the length of an interventional element|
    US20070156225A1|2003-12-23|2007-07-05|Xtent, Inc.|Automated control mechanisms and methods for custom length stent apparatus|
    US20050151304A1|2004-01-08|2005-07-14|Abbott Laboratories Vascular Enterprises Limited|Method of trimming a balloon of a balloon catheter|
    US20060089637A1|2004-10-14|2006-04-27|Werneth Randell L|Ablation catheter|
    EP1948139A4|2005-11-18|2012-04-04|3M Innovative Properties Co|Coatable compositions, coatings derived therefrom and microarrays having such coatings|
    US8066726B2|2004-11-23|2011-11-29|Boston Scientific Scimed, Inc.|Serpentine cutting blade for cutting balloon|
    US7736375B2|2004-11-29|2010-06-15|Boston Scientific Scimed, Inc.|Balloon catheter with controller depth incising blade|
    CA2585639C|2004-12-30|2012-12-04|Cook Incorporated|Catheter assembly with plaque cutting balloon|
    US20060184191A1|2005-02-11|2006-08-17|Boston Scientific Scimed, Inc.|Cutting balloon catheter having increased flexibility regions|
    US7586618B2|2005-02-28|2009-09-08|The Board Of Trustees Of The University Of Illinois|Distinguishing non-resonant four-wave-mixing noise in coherent stokes and anti-stokes Raman scattering|
    WO2006105121A2|2005-03-28|2006-10-05|Minnow Medical, Llc|Intraluminal electrical tissue characterization and tuned rf energy for selective treatment of atheroma and other target tissues|
    US7691086B2|2005-06-14|2010-04-06|Tengiz Tkebuchava|Catheter for introduction of medications to the tissues of a heart or other organ|
    US7850685B2|2005-06-20|2010-12-14|Medtronic Ablation Frontiers Llc|Ablation catheter|
    US8007508B2|2005-07-01|2011-08-30|Cox John A|System for tissue dissection and retraction|
    US8034066B2|2005-09-15|2011-10-11|Boston Scientific Scimed, Inc.|Multi-layer medical balloons|
    US7708753B2|2005-09-27|2010-05-04|Cook Incorporated|Balloon catheter with extendable dilation wire|
    US8123770B2|2005-11-01|2012-02-28|Cook Medical Technologies Llc|Angioplasty cutting device and method for treating a stenotic lesion in a body vessel|
    US20070181157A1|2006-02-07|2007-08-09|Dadourian Daniel G|Apparatus and methods for flushing medical devices|
    EP1984061B1|2006-02-14|2012-01-25|C.R.Bard, Inc.|Coaxial PTA balloon|
    DE102006008508A1|2006-02-23|2007-09-13|Siemens Ag|Medical visualization method for e.g. cardiological diagnosis of heart, involves storing recorded organ layer pictures with information about series of organ layer pictures and time period of recording in image data memory|
    SG11201506383VA|2013-03-08|2015-09-29|Limflow Gmbh|Methods and systems for providing or maintaining fluid flow through body passages|
    US7850710B2|2006-05-23|2010-12-14|St. Jude Medical Puerto Rico Llc|Puncture closure apparatuses, sealing plugs, and related methods|
    US9107736B2|2006-12-06|2015-08-18|Abbott Cardiovascular Systems Inc.|Highly trackable balloon catheter system and method for collapsing an expanded medical device|
    US8323307B2|2007-02-13|2012-12-04|Cook Medical Technologies Llc|Balloon catheter with dilating elements|
    US9050064B2|2007-04-27|2015-06-09|Cvdevices, Llc|Systems for engaging a bodily tissue and methods of using the same|
    JP2008295729A|2007-05-31|2008-12-11|Olympus Medical Systems Corp|Incision tool|
    US20080300610A1|2007-05-31|2008-12-04|Cook Incorporated|Device for treating hardened lesions and method of use thereof|
    WO2008153872A2|2007-06-08|2008-12-18|St. Jude Medical, Inc.|Devices for transcatheter prosthetic heart valve implantation and access closure|
    US9370642B2|2007-06-29|2016-06-21|J.W. Medical Systems Ltd.|Adjustable-length drug delivery balloon|
    GB0713497D0|2007-07-11|2007-08-22|Angiomed Ag|Device for catheter sheath retraction|
    US7879056B2|2007-10-11|2011-02-01|Keith Butterfield|Pleurabrade device|
    US8100860B2|2007-12-06|2012-01-24|Abbott Laboratories|Device and method for treating vulnerable plaque|
    JP5778427B2|2008-03-13|2015-09-16|クック・メディカル・テクノロジーズ・リミテッド・ライアビリティ・カンパニーＣｏｏｋ Ｍｅｄｉｃａｌ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ|Incision balloon with connector and expansion element|
    US20090306690A1|2008-06-05|2009-12-10|Cardiovascular Systems, Inc.|Abrasive nose cone with expandable cutting and sanding region for rotational atherectomy device|
    PL2293726T3|2008-06-10|2012-09-28|Bavaria Medizin Tech Gmbh|Scoring catheter for treating diseased heart valves|
    GB2461201B|2008-06-13|2011-07-06|Foundry Llc|Method and apparatus for joint distraction|
    US20100010521A1|2008-07-10|2010-01-14|Cook Incorporated|Cutting balloon with movable member|
    US8715227B2|2008-07-22|2014-05-06|Cook Medical Technologies Llc|Multi-stranded apparatus for treating a medical condition|
    US8226601B2|2008-11-12|2012-07-24|Sanovas, Inc.|Resector balloon system|
    US8712550B2|2008-12-30|2014-04-29|Biosense Webster, Inc.|Catheter with multiple electrode assemblies for use at or near tubular regions of the heart|
    EP2419167A1|2009-04-13|2012-02-22|Cook Medical Technologies LLC|Coated balloon catheter|
    US8911766B2|2009-06-26|2014-12-16|Abbott Cardiovascular Systems Inc.|Drug delivery compositions including nanoshells for triggered drug release|
    US8366661B2|2009-12-18|2013-02-05|Boston Scientific Scimed, Inc.|Medical device with expandable body for drug delivery by capsules|
    US8348987B2|2009-12-22|2013-01-08|Cook Medical Technologies Llc|Balloon with scoring member|
    WO2011081712A1|2009-12-31|2011-07-07|Boston Scientific Scimed, Inc.|Cryo activated drug delivery and cutting balloons|
    US20110184447A1|2010-01-26|2011-07-28|Warsaw Orthopedic, Inc.|Surgical cutting tool and method|
    US8211354B2|2010-05-18|2012-07-03|Cook Medical Technologies Llc|Balloon with integral retention of a dilation element|
    WO2012018899A1|2010-08-03|2012-02-09|Bayer Pharma Aktiengesellschaft|Balloon catheter with external delivery tube|
    US20120053485A1|2010-09-01|2012-03-01|Salient Surgical Technologies, Inc.|Catheter Having Needle And Expandable Support Member And Methods Of Use|
    US9327101B2|2010-09-17|2016-05-03|Abbott Cardiovascular Systems Inc.|Length and diameter adjustable balloon catheter|
    EP2616128A1|2010-09-17|2013-07-24|Abbott Cardiovascular Systems Inc.|Length and diameter adjustable balloon catheter|
    US9282991B2|2010-10-06|2016-03-15|Rex Medical, L.P.|Cutting wire assembly with coating for use with a catheter|
    US8685050B2|2010-10-06|2014-04-01|Rex Medical L.P.|Cutting wire assembly for use with a catheter|
    US8685049B2|2010-11-18|2014-04-01|Rex Medical L.P.|Cutting wire assembly for use with a catheter|
    US8702736B2|2010-11-22|2014-04-22|Rex Medical L.P.|Cutting wire assembly for use with a catheter|
    WO2012078465A1|2010-12-08|2012-06-14|Boston Scientific Scimed, Inc.|Drug eluting balloons with ability for double treatment|
    US8491615B2|2010-12-29|2013-07-23|Boston Scientific Scimed, Inc.|Cutting balloon catheter|
    US8597239B2|2011-03-01|2013-12-03|Sanovas, Inc.|Abrading balloon catheter for extravasated drug delivery|
    ES2791766T3|2011-09-13|2020-11-05|Pigott John P|Intravascular catheter having an expandable incision portion|
    US10610255B2|2011-09-13|2020-04-07|John P. Pigott|Intravascular catheter having an expandable incising portion and medication delivery system|
    US9364284B2|2011-10-12|2016-06-14|Boston Scientific Scimed, Inc.|Method of making an off-wall spacer cage|
    US9079000B2|2011-10-18|2015-07-14|Boston Scientific Scimed, Inc.|Integrated crossing balloon catheter|
    US9364255B2|2011-11-09|2016-06-14|Boston Scientific Scimed, Inc.|Medical cutting devices and methods of use|
    US8574248B2|2011-12-12|2013-11-05|Kassab Kughn Endovascular Devices|Catheter system with balloon-mounted plaque-modifying elements|
    WO2013096922A1|2011-12-23|2013-06-27|Vessix Vascular, Inc.|Methods and apparatuses for remodeling tissue of or adjacent to a body passage|
    EP3711810A1|2012-04-19|2020-09-23|Fractyl Laboratories, Inc.|Tissue expansion devices, systems and methods|
    US8740849B1|2012-10-29|2014-06-03|Ablative Solutions, Inc.|Peri-vascular tissue ablation catheter with support structures|
    CA2892517A1|2012-12-31|2014-07-03|C.R. Bard, Inc.|Balloon catheter with adjustable inner member|
    CN105228684A|2013-03-12|2016-01-06|雅培心血管系统有限公司|For length and the adjustable foley's tube of diameter of delivering medicament|
    US9320530B2|2013-03-13|2016-04-26|The Spectranetics Corporation|Assisted cutting balloon|
    US20140364896A1|2013-06-07|2014-12-11|Abott Cardiovascular Systems, Inc.|Device, system, and method for thrombus retrieval|
    US10639061B2|2013-11-11|2020-05-05|Cook Medical Technologies Llc|Devices and methods for modifying veins and other bodily vessels|
    WO2015190578A1|2014-06-13|2015-12-17|テルモ株式会社|Medical device|
    WO2015195606A1|2014-06-16|2015-12-23|Pigott John P|Intravascular catheter having an expandable incising portion and drug delivery mechanism|
    US9545263B2|2014-06-19|2017-01-17|Limflow Gmbh|Devices and methods for treating lower extremity vasculature|
    US10478213B2|2015-06-25|2019-11-19|Covidien Lp|Tissue-removing catheter with adjustable cross-sectional dimension|
    EP3135206B1|2015-08-31|2020-01-15|Gefässpraxis Dr. Erpen AG|Device for treating varicose veins|US20040111108A1|2001-11-09|2004-06-10|Farnan Robert C.|Balloon catheter with non-deployable stent|
    ES2320742T3|2001-11-09|2009-05-28|Angioscore, Inc.|BALL CATHETER WITH NON-DISPLAYABLE ENDOPROTESIS.|
    US8080026B2|2003-01-21|2011-12-20|Angioscore, Inc.|Apparatus and methods for treating hardened vascular lesions|
    US10076641B2|2005-05-11|2018-09-18|The Spectranetics Corporation|Methods and systems for delivering substances into luminal walls|
    EP2254641B1|2008-03-21|2016-09-21|Cagent Vascular, LLC|Device for pre-angioplasty serration and dilatation|
    US9480826B2|2008-03-21|2016-11-01|Cagent Vascular, Llc|Intravascular device|
    US11219750B2|2008-03-21|2022-01-11|Cagent Vascular, Inc.|System and method for plaque serration|
    EP2380604A1|2010-04-19|2011-10-26|InnoRa Gmbh|Improved coating formulations for scoring or cutting balloon catheters|
    US8632559B2|2010-09-21|2014-01-21|Angioscore, Inc.|Method and system for treating valve stenosis|
    US20160310163A1|2011-09-13|2016-10-27|John P. Pigott|Intravascular catheter having an expandable incising portion and embolic protection device|
    US20170156749A1|2011-09-13|2017-06-08|John P. Pigott|Intravascular catheter having an expandable incising portion and abrasive surfaces|
    US10610255B2|2011-09-13|2020-04-07|John P. Pigott|Intravascular catheter having an expandable incising portion and medication delivery system|
    US10463387B2|2011-09-13|2019-11-05|John P. Pigott|Intravascular catheter having an expandable incising portion for incising atherosclerotic material located in a blood vessel|
    US20170209160A1|2011-09-13|2017-07-27|John P. Pigott|Intravascular catheter having an expandable incising portion and grating tool|
    ES2791766T3|2011-09-13|2020-11-05|Pigott John P|Intravascular catheter having an expandable incision portion|
    EP3628247A1|2012-02-07|2020-04-01|Intervene, Inc.|System for endoluminal valve creation|
    EP2943151B1|2013-01-10|2017-07-19|Intervene, Inc.|System for endoluminal valve creation|
    WO2014141226A1|2013-03-15|2014-09-18|National University Of Ireland|A device suitable for removing matter from inside the lumen and the wall of a body lumen|
    US9445801B2|2013-03-15|2016-09-20|Cook Medical Technologies Llc|Medical device with selective rigidity|
    US10130798B2|2013-07-15|2018-11-20|John P. Pigott|Balloon catheter having a retractable sheath and locking mechanism|
    US10315014B2|2013-07-15|2019-06-11|John P. Pigott|Balloon catheter having a retractable sheath and locking mechanism with balloon recapture element|
    US10828471B2|2013-07-15|2020-11-10|John P. Pigott|Balloon catheter having a retractable sheath|
    US11202892B2|2013-07-15|2021-12-21|John P. Pigott|Balloon catheter having a retractable sheath|
    WO2015048565A2|2013-09-27|2015-04-02|Intervene, Inc.|Visualization devices, systems, and methods for informing intravascular procedures on blood vessel valves|
    US10117668B2|2013-10-08|2018-11-06|The Spectranetics Corporation|Balloon catheter with non-deployable stent having improved stability|
    WO2015089422A1|2013-12-12|2015-06-18|Case Western Reserve University|Device for collecting a biological sample|
    US10188419B2|2014-03-24|2019-01-29|Intervene, Inc.|Visualization devices for use during percutaneous tissue dissection and associated systems and methods|
    EP3151901A4|2014-06-03|2018-02-21|Pigott, John, P.|Intravascular catheter with drug delivery system|
    WO2015195606A1|2014-06-16|2015-12-23|Pigott John P|Intravascular catheter having an expandable incising portion and drug delivery mechanism|
    CN104068918B|2014-07-14|2015-07-22|业聚医疗器械有限公司|Catheter with atherosclerotic plaque cutting and sucking function|
    CA2969535A1|2014-11-03|2016-05-12|Cagent Vascular, Llc|Serration balloon|
    EP3017775A1|2014-11-07|2016-05-11|National University of Ireland, Galway|A thrombectomy device|
    CA2969579A1|2014-12-03|2016-06-09|PAVmed Inc.|Systems and methods for percutaneous division of fibrous structures|
    EP3232953A2|2014-12-16|2017-10-25|Intervene, Inc.|Intravascular devices, systems, and methods for the controlled dissection of body lumens|
    WO2016115102A1|2015-01-13|2016-07-21|Pigott John P|Intravascular catheter having an expandable portion|
    US10603069B2|2015-01-13|2020-03-31|John P. Pigott|Intravascular catheter balloon device having a tool for atherectomy or an incising portion for atheromatous plaque scoring|
    US10456160B2|2015-03-09|2019-10-29|Teleflex Innovations S.À.R.L.|Stenotic region scoring assembly and method|
    KR101835678B1|2015-09-04|2018-03-08|재단법인 아산사회복지재단|retractable flexible cautery device|
    WO2017049227A2|2015-09-17|2017-03-23|Cagent Vascular, Llc|Wedge dissectors for a medical ballon|
    US10646247B2|2016-04-01|2020-05-12|Intervene, Inc.|Intraluminal tissue modifying systems and associated devices and methods|
    JP2019146601A|2016-07-13|2019-09-05|テルモ株式会社|Cutting device and treatment method|
    JP2019535481A|2016-11-16|2019-12-12|ケイジェント ヴァスキュラー， エルエルシーＣａｇｅｎｔ Ｖａｓｃｕｌａｒ， Ｌｌｃ|System and method for inserting drug into tissue via serration|
    WO2020191400A1|2019-03-21|2020-09-24|The General Hospital Corporation|Systems and methods for catheter based light delivery|
    CN111568497B|2020-05-13|2021-03-19|黑龙江省医院|Thrombus thrombolysis clearing device and use method thereof|
    法律状态:
    2018-12-11| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2019-10-01| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2020-10-20| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2020-12-29| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/09/2012, OBSERVADAS AS CONDICOES LEGAIS. |
    2021-08-17| B25A| Requested transfer of rights approved|Owner name: VENTUREMED GROUP, INC. (US) |
    优先权:
    申请号 | 申请日 | 专利标题
    US201161534018P| true| 2011-09-13|2011-09-13|
    US61/534,018|2011-09-13|
    PCT/US2012/055079|WO2013040160A1|2011-09-13|2012-09-13|Intravascular catheter having an expandable incising portion|
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